The plant typhonium flagelliforme, commonly known as rodent tuber in malaysia, is often used as a health supplement and traditional remedy for alternative cancer therapies, including leukemia. This page was last edited on 16 december 2019, at 17. Its active ingredients including phytol and its derivative, hexadecanoic acid, 1hexadecene, and pheophorbide related compoundshave shown some promising results as. The genus typhonium suggested having about 50 species from india to polynesia and distributed 9 species in china 3. In vitro studies on continuous culture of continuous culture of human lymphoblasts cems showed that typhonium flagelliforme tf increases apoptosis. The situation for chinese herbalists is complicated by the fact that the report of ephedrine in pinellia has been from tests with the source material pinellia ternata referred to as northern banxia, pictured. Typhonium flagelliforme inhibits the proliferation of murine. Blume diketahui memiliki aktivitas antikanker, detoksifikasi, antiinflamasi, antivirus dan antibakteri. This plant had shown to induce antiproliferative effect as well as.
Blume araceae is a malaysian plant used locally to combat cancer. In vitro propagation of typhonium flagelliforme lodd blume. Typhonium flagelliforme is a prominent plant candidate from aroid family, endowing various curative properties against a variety of illness and infections. All structured data from the file and property namespaces is available under the. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader. Typhonium flagelliforme is a species of flowering plant in the family araceae typhonium flagelliforme is native to guangdong, guangxi, yunnan, bangladesh, bhutan. Rodent tuber keladi tikus obat kanker pengobatan kanker. Rodent tuber grows wild in wasteland and is native to the south east asian countries. It has been used for treating internal injuries and edema. In vitro propagation of typhonium flagelliforme lodd. To download the pdf, click the download link below. The rhizomes of the plant have traditionally been used as an expectorant for coughs and as treatment for other pulmonary ailments.
The major aim of this study was to investigate the effect of. Rodent tuber typhonium flagelliforme cut open to show presence of tiny insects inside. Oct 30, 2018 typhonium flagelliforme in world checklist of selected plant families. Typhonium flagelliforme, previously mistakenly referred as typhonium divaricatum nicolson and sivadasan, 1981, is commonly known as rodent tuber in malaysia. Typhonium flagelliforme inhibits cancer cell growth in. The antioxidant and antibacterial activity of different extracts from of typhonium flagelliforme l. Even one variety of typhonium, typhonium flagelliforme, is used as banxia in china. Compounds in mutant clones of rodent tuber typhonium flagelliforme lodd.
Typhonium flagelliforme, phytochemicals, traditional medicine. The situation for chinese herbalists is complicated by the fact that the report of ephedrine in pinellia has been from tests with the source material pinellia ternata referred to as northern banxia, pictured upper left while most of the pinellia used in china and in the west is actually from a related plant that has the same uses. It has an oblong whitish tuber, triangular leaves ad a spathe. Typhonium flagelliforme is currently being investigated for its cancer curing properties and has long been used as a traditional medicine in parts of asia. In silico screening of mutated kras inhibitors from. Antiproliferation activity of tuber protein from typhonium flagelliforme lodd. This plant had shown to induce antiproliferative effect as well as apoptosis in cancer cells.
The plant typhonium flagelliforme, commonly known as rodent tuber in malaysia, is often used as a health supplement and traditional remedy. S2, wahono s3 1faculty of pharmacy, pancasila university, jakarta 12640, indonesia 2department of chemistry, fmipa, university of indonesia, depok 1624, indonesia 3agency for the assessment and apllication of technology, indonesia bppt. To date, there has been no literature reported on the mechanism of typhonium flagelliforme and its effects on leukemia. An typhonium flagelliforme in nahilalakip ha genus nga typhonium, ngan familia nga araceae. Isolation and identification of chemical compounds in n. Original article molecular authentication of pinelliae. Pdf antiproliferation activity of tuber protein from. Typhonium flagelliforme is a species of flowering plant in the family araceae typhonium flagelliforme is native to guangdong, guangxi, yunnan, bangladesh, bhutan, cambodia, india, indonesia, laos. Typhonium flagelliforme patterned leaf form aga190001 aug. Researchers have reported its activity in lung cancer as a whole extract in. K ras is an oncogenic gtpase responsible for at least 1525% of all nonsmall cell lung cancer cases worldwide. In this study, the leaves of keladi tikus plant were extracted using methanol and then partitioned using nhexane, ethylacetate, and nbuthanol sequentially. Alternatively, you can also download the pdf file directly to your computer, from where it can be opened using a pdf reader. Investigations of antioxidant and antibacterial activities.
Jan 01, 2001 read cytotoxic activity of typhonium flagelliforme araceae, phytotherapy research on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. A cerebroside, with significant antihepatotoxic activity and phenylpropanoid glycosides isolated from flagelliforme typhyonium for the first time huang et al. To determine the effects of different strength of murashige and skoog ms media full. Antibacterial and antioxidant activities of typhonium flagelliforme lodd. Jurnal full paper teknologi article history cytotoxicity effects of typhonium flagelliforme received and clinacanthus nutans on.
Rodent tuber or typhonium flagelliforme extract and other herbs combination help in the detoxification of the blood system. Hence, the antileukemia effect of typhonium flagelliforme was investigated in. Fraction from typhonium flagelliforme tuber citeseerx. Pdf typhonium flagelliforme decreases protein expression. It is being used traditionally in malaysia to treat cancer. The plant typhonium flagelliforme araceae, commonly known as the rodent tuber, is often included as an essential ingredient in various herbal remedies recommended for cancer therapies in malaysia. The plant list includes a further 14 scientific plant names of. Nevertheless, it is a rarely seen plant in cultivation and not often seen in collections. Analysis of preliminary phytochemical screening of. Introduction rodent tuber typhonium flagelliforme lodd. The objective of this study was to evaluate whether tf syrup tfs could decrease her2 neu and bcl2 expression as well as breast cancer volume bcv in mice. Typhonium flagelliforme inhibits cancer cell growth in vitro.
Antileukemic effects of typhonium flagelliforme on human. Ayesha fatima department of pharmaceutical technology, faculty of. In vitro ultramorphological assessment of apoptosis on cemss. Nevertheless, it is a rarely seen plant in cultivation and. In vitro anticancer activity was assayed by mtt method on widr colon cancer cells. S2, wahono s3 1faculty of pharmacy, pancasila university, jakarta 12640, indonesia. Cytotoxic activity of typhonium flagelliforme araceae. These were murashige and skoog ms, nitsch and nitsch nn, gamborg b5 gb5 and white w of which ms medium was found to be the best medium for in vitro culture of t.
Flower color is purplelavender and blooms in summer. Bap is a cytokinintype pgr that is effective in inducing the production and propagation of buds from bud eyes gunawan, 1987. How typhonium trilobatum is effective for various diseases is listed in. Rodent tuber, keladi tikus, tu ban xia or lao shu yu botanical name. The board of trustees of the royal botanic gardens, kew. Pdf antibacterial and antioxidant activities of typhonium. Typhonium flagelliforme extract and other herbs combine help in the detoxification of the blood system. The plant list includes 115 scientific plant names of species rank for the genus typhonium. Files are available under licenses specified on their description page. Pdf typhonium flagelliforme is a prominent plant candidate from aroid family, endowing various curative properties against a variety of illness and. Enhancement of the contents of anticancer bioactive.
Hence, the antileukemia effect of typhonium flagelliforme was investigated in vitro and in vivo leukemic model. Pinellia refers to the tuber of pinellia ternata see figure 1, known to the chinese as banxia. Dari beberapa penelitian disebutkan bahwa daun keladi tikus dimanfaatkan sebagai terapi alternatif pada kanker payudara, kolon, paruparu, serviks dan leukemia masood, dkk. In this study, the leaves of keladi tikus plant were extracted using. This formula contains ribosome in acting protein rip, anti oxidant, and.
An in vitro culture system was developed for typhonium flagelliforme using buds from the rhizomes. Typhonium flagelliforme from the family araceae is locally known as rodent tuber. In order to evaluate its antiproliferative activity in vitro and to possibly identify the active chemical constituents, a bioactivity guided study was conducted on the extracts of this plant. Typhonium plus complementary alternative cancer treatment. Keladi tikus rodent tuber typhonium flagelliforme lood bl. Staminodes variable, spatulate to filamentous or variously reduced. Uses, benefits, cures, side effects, nutrients in typhonium trilobatum. Typhonium trilobatum herb uses, benefits, cures, side. Lung cancer of both types is increasing with an alarming rate due to smoking habits in malaysia among men and women.
Typhonium flagelliforme keladi tikus is one such plant that is found locally in malaysia that has been studied for its inhibition of proliferation in human lung cancer cell line. Names of typhonium trilobatum in various languages of the world are also given. Supervised classification karakter morfologi tanaman keladi. Typhonium flagelliforme keladi tikus is a herbal plant grows in east asia as traditional medicine to combat cancer. Antibacterial and antioxidant activity of keladi tikus leaves extract typhonium flagelliforme lodd blume author links open overlay panelyunaharafarida. Detection of gammairradiated mutant of rodent tuber. Typhonium flagelliforme keladi tikus typhonium flagelliforme can be easily found in the indonesian forest. Typhonium flagelliforme international aroid society. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs alternatively, you can download the pdf file. Rodent tuber has a broad array of bioactive compounds with anticancer activity against lung, breast2, liver3, blood4. This page was last edited on 8 december 2019, at 15. Typhonium flagelliforme inflorescence cut open to show.
Typhonium flagelliforme rodent tuber is a herbal plant which grows up to 30cm in height. Pages in category typhonium the following 4 pages are in this category, out of 4 total. Pengaruh kombinasi ekstrak sirih merah piper crocatum. All structured data from the file and property namespaces is available under the creative commons cc0 license. The plant typhonium flagelliforme araceae, commonly known as the rodent tuber, is often included as an essential ingredient in various herbal remedies recommended for cancer. Typhonium in world checklist of selected plant families. This tropical plant found in damp, shady habitats and population of south east asian countries used it as alternative curative health supplement. Supervised classification karakter morfologi tanaman. Nov 21, 2017 rodent tuber typhonium flagelliforme cut open to show presence of tiny insects inside.
Biological activity test of extract and fraction there of. Typhonium flagelliforme in world checklist of selected plant families. List of various diseases cured by typhonium trilobatum. Araceae commonly called rodent tuber was assessed towards different. Images and links for typhonium flagelliforme from the international aroid society. Various extracts prepared from either the roots, tubers, stems or leaves were tested for cytotoxic activity on murine p388 leukaemia cells using the mtt assay method. The raw material is somewhat toxic, being highly irritating to tissues that it contacts, and is mainly used externally. Female flowers 1loculed with 1 or 2or 3 orthotropous basal ovules. Typhonium plus is a formula of selective herbs extract which in synergy strengthening works of typhonium flagelliforme. Abstractobjectiveto determine the inhibition activity of typhonium flagelliforme lodd.
Micropropagation of rodent tuber typhonium flagelliforme lodd. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs. Typhonium flagelliforme keladi tikus, from familia araceae, is widely used as an alternative therapy to treat various cancer. Typhonium flagelliforme inhibits the proliferation of. Typhonium flagelliforme tf is a tropical plant, traditionally used by the ethnic population of malaysia for the cure of various cancers. Typhonium flagelliforme araceae is a medicinal herb which is endowed with curative properties against a variety of illness including injuries, oedema, coughs, pulmonary ailments, bleeding and cancer. Typhonium flagelliforme or keladi tikus is a local. In silico screening of mutated kras inhibitors from malaysian typhonium flagelliforme for nonsmall cell lung cancer. Lung cancer of both types is increasing with an alarming rate due to smoking habits in. In vitro ultramorphological assessment of apoptosis on. Typhonium trilobatum herb uses, benefits, cures, side effects. Analysis of preliminary phytochemical screening of typhonium. Pdf the effects of different strength of ms media in.
1005 349 1114 849 203 53 1520 781 7 620 1090 1464 1039 349 1193 264 641 23 1328 1290 1479 1374 27 1348 410 535 818 325 1119 429 28